Product Data Sheet

Loncastuximab tesirine

Catalog No. A30067

main product photo
Loncastuximab tesirine is an antibody-drug conjugate (ADC) targeting the cluster of differentiation 19 (CD19) antigen. This compound comprises the Loncastuximab antibody linked to Tesirine, a potent cytotoxic agent. Upon binding to CD19, Loncastuximab tesirine is internalized, leading to apoptosis in malignant B-cells. This reagent is primarily utilized in research focused on diffuse large B-cell lymphoma and related hematological malignancies.
Chemical Information
Catalog NumA30067
M. Wt147000 (average)
Formula
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1879918-31-6
SynonymsLoncastuximab tesirine-lpyl; ADCT-402
SMILES[Loncastuximab tesirine]
Biological Activity
DescriptionLoncastuximab tesirine is an antibody-drug conjugate (ADC) targeting the cluster of differentiation 19 (CD19) antigen. This compound comprises the Loncastuximab antibody linked to Tesirine, a potent cytotoxic agent. Upon binding to CD19, Loncastuximab tesirine is internalized, leading to apoptosis in malignant B-cells. This reagent is primarily utilized in research focused on diffuse large B-cell lymphoma and related hematological malignancies.
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SHIPPING AND STORAGE
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