Product Data Sheet

Thalidomide-NH-CH2-COOH

Catalog No. A30235

main product photo
Thalidomide-NH-CH2-COOH is a Thalidomide-derived ligand that specifically targets the cereblon (CRBN) protein, facilitating its recruitment in various biological processes. This compound serves as a crucial building block for the development of PROTACs, allowing researchers to design targeted protein degradation strategies. Its application is significant in the study of protein homeostasis and the therapeutic potential of targeted protein modulation.
Chemical Information
Catalog NumA30235
M. Wt331.28
FormulaC15H13N3O6
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.927670-97-1
Synonyms
SMILESO=C(O)CNC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O
Biological Activity
DescriptionThalidomide-NH-CH2-COOH is a Thalidomide-derived ligand that specifically targets the cereblon (CRBN) protein, facilitating its recruitment in various biological processes. This compound serves as a crucial building block for the development of PROTACs, allowing researchers to design targeted protein degradation strategies. Its application is significant in the study of protein homeostasis and the therapeutic potential of targeted protein modulation.
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SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.