Product Data Sheet
L-Asparagine-15N2 monohydrate
Catalog No. A30253
L-Asparagine-15N2 monohydrate is a stable isotope-labeled analog of the amino acid L-Asparagine. It is critical for leukemic cells and serves as a substrate for the enzyme L-Asparaginase, which facilitates the depletion of asparagine and glutamine, thereby inhibiting protein biosynthesis in lymphoblasts. This process leads to reduced RNA and DNA synthesis and triggers apoptosis, making L-Asparaginase a valuable anti-leukemic agent. L-Asparagine-15N2 monohydrate is applicable in research focused on childhood acute lymphoblastic leukemia, acting as a biomarker and sensor for in-depth studies of cell metabolism in this context.
Chemical Information
| Catalog Num | A30253 |
|---|---|
| M. Wt | 152.12 |
| Formula | C4H1015N2O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 287484-32-6 |
| Synonyms | (-)-Asparagine-15N2 monohydrate; Asn-15N2 monohydrate; Asparamide-15N2 monohydrate |
| SMILES | [15NH2]C(C[C@H]([15NH2])C(O)=O)=O.[H]O[H] |
Biological Activity
| Description | L-Asparagine-15N2 monohydrate is a stable isotope-labeled analog of the amino acid L-Asparagine. It is critical for leukemic cells and serves as a substrate for the enzyme L-Asparaginase, which facilitates the depletion of asparagine and glutamine, thereby inhibiting protein biosynthesis in lymphoblasts. This process leads to reduced RNA and DNA synthesis and triggers apoptosis, making L-Asparaginase a valuable anti-leukemic agent. L-Asparagine-15N2 monohydrate is applicable in research focused on childhood acute lymphoblastic leukemia, acting as a biomarker and sensor for in-depth studies of cell metabolism in this context. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
