Miltirone
Catalog No. A30275

Miltirone is a partial agonist of the central benzodiazepine receptor, exhibiting an IC50 value of 0.3 μM. This natural compound, derived from the root of Salvia miltiorrhiza, demonstrates significant biological activity by inducing ROS- and p53-dependent apoptosis. Additionally, Miltirone effectively inhibits carboxylesterase 2 (CES2) with a Ki of 0.04 μM and the main protease (Mpro) of SARS-CoV, making it valuable for research involving apoptosis, enzymatic regulation, and virology.
Chemical Information
| Catalog Num | A30275 |
|---|---|
| M. Wt | 282.38 |
| Formula | C19H22O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 27210-57-7 |
| Synonyms | Rosmariquinone |
| SMILES | O=C1C(C(C)C)=CC2=C(C3=C(C=C2)C(C)(C)CCC3)C1=O |
Biological Activity
| Description | Miltirone is a partial agonist of the central benzodiazepine receptor, exhibiting an IC50 value of 0.3 μM. This natural compound, derived from the root of Salvia miltiorrhiza, demonstrates significant biological activity by inducing ROS- and p53-dependent apoptosis. Additionally, Miltirone effectively inhibits carboxylesterase 2 (CES2) with a Ki of 0.04 μM and the main protease (Mpro) of SARS-CoV, making it valuable for research involving apoptosis, enzymatic regulation, and virology. |
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RETURN POLICY
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


