Product Data Sheet
Metformin-d6 hydrochloride
Catalog No. A30281
Metformin-d6 hydrochloride is a stable isotope-labeled form of Metformin hydrochloride, primarily targeting the mitochondrial respiratory chain. It is known for its ability to activate AMPK, thereby enhancing insulin sensitivity and providing insights into type 2 diabetes research. Additionally, Metformin-d6 hydrochloride mitigates oxidative and nitrosative stress, inflammation, and apoptosis associated with liver ischemia/reperfusion injury. The compound also influences autophagy-related protein expression by modulating the mTOR signaling pathway, facilitating tumor cell autophagy, and exerting anti-tumor effects in renal cell carcinoma models.
Chemical Information
| Catalog Num | A30281 |
|---|---|
| M. Wt | 171.66 |
| Formula | C4H6D6ClN5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1185166-01-1 |
| Synonyms | 1,1-Dimethylbiguanide-d6 hydrochloride |
| SMILES | NC(NC(N(C([2H])([2H])[2H])C([2H])([2H])[2H])=N)=N.[H]Cl |
Biological Activity
| Description | Metformin-d6 hydrochloride is a stable isotope-labeled form of Metformin hydrochloride, primarily targeting the mitochondrial respiratory chain. It is known for its ability to activate AMPK, thereby enhancing insulin sensitivity and providing insights into type 2 diabetes research. Additionally, Metformin-d6 hydrochloride mitigates oxidative and nitrosative stress, inflammation, and apoptosis associated with liver ischemia/reperfusion injury. The compound also influences autophagy-related protein expression by modulating the mTOR signaling pathway, facilitating tumor cell autophagy, and exerting anti-tumor effects in renal cell carcinoma models. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
