Product Data Sheet
Irigenin
Catalog No. A30290
Irigenin is an inhibitor of EDA-integrin interactions, specifically targeting α9β1 and α4β1 integrins by blocking their binding sites on the C-C loop of Extra Domain A (EDA). This compound exhibits significant anti-cancer properties, particularly in gastric cancer cells, where it enhances TRAIL-induced apoptosis by increasing the expression of pro-apoptotic molecules. Irigenin may be valuable in cancer research, particularly in studies focused on metastasis and apoptosis modulation.
Chemical Information
| Catalog Num | A30290 |
|---|---|
| M. Wt | 360.31 |
| Formula | C18H16O8 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 548-76-5 |
| Synonyms | |
| SMILES | O=C1C(C2=CC(OC)=C(OC)C(O)=C2)=COC3=CC(O)=C(OC)C(O)=C13 |
Biological Activity
| Description | Irigenin is an inhibitor of EDA-integrin interactions, specifically targeting α9β1 and α4β1 integrins by blocking their binding sites on the C-C loop of Extra Domain A (EDA). This compound exhibits significant anti-cancer properties, particularly in gastric cancer cells, where it enhances TRAIL-induced apoptosis by increasing the expression of pro-apoptotic molecules. Irigenin may be valuable in cancer research, particularly in studies focused on metastasis and apoptosis modulation. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
