Product Data Sheet
BDE 47
Catalog No. A30392
BDE 47 is a JNK activator that targets mitochondria to inhibit mitochondrial oxidative phosphorylation (OXPHOS). This compound decreases mitochondrial membrane potential (MMP) and induces apoptosis in embryonic cells. Additionally, BDE 47 triggers the generation of reactive oxygen species (ROS) and activates the JNK signaling pathway, demonstrating embryonic developmental toxicity in zebrafish models. Its unique properties make it a valuable tool for research on oxidative stress and developmental biology.
Chemical Information
| Catalog Num | A30392 |
|---|---|
| M. Wt | 485.79 |
| Formula | C12H6Br4O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 5436-43-1 |
| Synonyms | |
| SMILES | BrC1=CC=C(C(Br)=C1)OC2=CC=C(C=C2Br)Br |
Biological Activity
| Description | BDE 47 is a JNK activator that targets mitochondria to inhibit mitochondrial oxidative phosphorylation (OXPHOS). This compound decreases mitochondrial membrane potential (MMP) and induces apoptosis in embryonic cells. Additionally, BDE 47 triggers the generation of reactive oxygen species (ROS) and activates the JNK signaling pathway, demonstrating embryonic developmental toxicity in zebrafish models. Its unique properties make it a valuable tool for research on oxidative stress and developmental biology. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
