Product Data Sheet
Melatonin-d3
Catalog No. A30450
Melatonin-d3 is a deuterium-labeled form of melatonin, a hormone produced by the pineal gland that activates melatonin receptors. This compound is known for its critical role in regulating sleep and exhibits significant antioxidative and anti-inflammatory effects. Additionally, melatonin functions as a selective ATF-6 inhibitor, inducing apoptosis in human hepatoma cells through COX-2 downregulation. It also mitigates palmitic acid-induced apoptosis in mouse granulosa cells via endoplasmic reticulum stress mechanisms, making it valuable for research in cellular signaling and metabolic disorders.
Chemical Information
| Catalog Num | A30450 |
|---|---|
| M. Wt | 235.30 |
| Formula | C13H13D3N2O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 90735-69-6 |
| Synonyms | N-Acetyl-5-methoxytryptamine-d3 |
| SMILES | O=C(NCCC1=CNC2=C1C=C(OC)C=C2)C([2H])([2H])[2H] |
Biological Activity
| Description | Melatonin-d3 is a deuterium-labeled form of melatonin, a hormone produced by the pineal gland that activates melatonin receptors. This compound is known for its critical role in regulating sleep and exhibits significant antioxidative and anti-inflammatory effects. Additionally, melatonin functions as a selective ATF-6 inhibitor, inducing apoptosis in human hepatoma cells through COX-2 downregulation. It also mitigates palmitic acid-induced apoptosis in mouse granulosa cells via endoplasmic reticulum stress mechanisms, making it valuable for research in cellular signaling and metabolic disorders. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
