Product Data Sheet
LCH-7749944
Catalog No. A30458
LCH-7749944 is a potent inhibitor of PAK4, demonstrating an IC50 of 14.93 μM. It effectively inhibits the proliferation of human gastric cancer cells by downregulating the PAK4/c-Src/EGFR/cyclin D1 signaling pathway and induces apoptosis in these cells. This reagent is valuable for research focused on cancer biology and therapeutic strategies targeting PAK4-related pathways.
Chemical Information
| Catalog Num | A30458 |
|---|---|
| M. Wt | 350.41 |
| Formula | C20H22N4O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 796888-12-5 |
| Synonyms | GNF-PF-2356 |
| SMILES | COC1=CC(NC2=NC(NCC3OCCC3)=C4C=CC=CC4=N2)=CC=C1 |
Biological Activity
| Description | LCH-7749944 is a potent inhibitor of PAK4, demonstrating an IC50 of 14.93 μM. It effectively inhibits the proliferation of human gastric cancer cells by downregulating the PAK4/c-Src/EGFR/cyclin D1 signaling pathway and induces apoptosis in these cells. This reagent is valuable for research focused on cancer biology and therapeutic strategies targeting PAK4-related pathways. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
