Product Data Sheet

Tricetin

Catalog No. A30478

main product photo
Tricetin is a competitive inhibitor of the Keap1-Nrf2 protein-protein interaction (PPI). This compound exhibits neuroprotective effects by activating the Nrf2/HO-1 signaling pathway, which mitigates 6-OHDA-induced neurotoxicity in models of Parkinson's disease. Its mechanism of action helps to prevent apoptosis through mitochondrial pathways, making it a valuable reagent for research into neurodegenerative diseases and oxidative stress response.
Chemical Information
Catalog NumA30478
M. Wt302.24
FormulaC15H10O7
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.520-31-0
Synonyms
SMILESO=C1C=C(C2=CC(O)=C(O)C(O)=C2)OC3=CC(O)=CC(O)=C13
Biological Activity
DescriptionTricetin is a competitive inhibitor of the Keap1-Nrf2 protein-protein interaction (PPI). This compound exhibits neuroprotective effects by activating the Nrf2/HO-1 signaling pathway, which mitigates 6-OHDA-induced neurotoxicity in models of Parkinson's disease. Its mechanism of action helps to prevent apoptosis through mitochondrial pathways, making it a valuable reagent for research into neurodegenerative diseases and oxidative stress response.
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