Product Data Sheet
Yamogenin
Catalog No. A30539
Yamogenin, a diastereomer of diosgenin, acts as an antagonist of the liver X receptor (LXR). It has been shown to inhibit triacylglyceride (TG) accumulation in HepG2 hepatocytes by downregulating fatty acid synthesis gene expression. This steroidal saponin exhibits in vitro cytotoxic, antioxidant, and antimicrobial properties, inducing cell death through both extrinsic and intrinsic apoptosis pathways. Yamogenin has potential applications in research focused on gastric cancer.
Chemical Information
| Catalog Num | A30539 |
|---|---|
| M. Wt | 414.62 |
| Formula | C27H42O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 512-06-1 |
| Synonyms | Neodiosgenin |
| SMILES | O[C@]1([H])CC2=CC[C@]3([H])[C@@](CC[C@@]4(C)[C@@]3([H])C[C@@]5([H])[C@]4([H])[C@@](C)([H])[C@@]6(CC[C@]([H])(C)CO6)O5)([H])[C@@]2(C)CC1 |
Biological Activity
| Description | Yamogenin, a diastereomer of diosgenin, acts as an antagonist of the liver X receptor (LXR). It has been shown to inhibit triacylglyceride (TG) accumulation in HepG2 hepatocytes by downregulating fatty acid synthesis gene expression. This steroidal saponin exhibits in vitro cytotoxic, antioxidant, and antimicrobial properties, inducing cell death through both extrinsic and intrinsic apoptosis pathways. Yamogenin has potential applications in research focused on gastric cancer. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
