Product Data Sheet

Dasatinib-d8

Catalog No. A30589

main product photo
Dasatinib-d8 is a deuterium-labeled analog of Dasatinib, a dual inhibitor of Bcr-Abl and Src family tyrosine kinases. This stable isotope is primarily utilized in pharmacokinetic studies and metabolic research, allowing for precise measurement of drug disposition and biological effects. Its application facilitates investigations into the mechanisms of action and resistance patterns associated with tyrosine kinase inhibitors in cancer therapy.
Chemical Information
Catalog NumA30589
M. Wt496.05
FormulaC22H18D8ClN7O2S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1132093-70-9
SynonymsBMS-354825-d8
SMILESO=C(C1=CN=C(NC2=NC(C)=NC(N3C([2H])([2H])C([2H])([2H])N(CCO)C([2H])([2H])C3([2H])[2H])=C2)S1)NC4=C(C)C=CC=C4Cl
Biological Activity
DescriptionDasatinib-d8 is a deuterium-labeled analog of Dasatinib, a dual inhibitor of Bcr-Abl and Src family tyrosine kinases. This stable isotope is primarily utilized in pharmacokinetic studies and metabolic research, allowing for precise measurement of drug disposition and biological effects. Its application facilitates investigations into the mechanisms of action and resistance patterns associated with tyrosine kinase inhibitors in cancer therapy.
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SHIPPING AND STORAGE
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