Product Data Sheet

CMLD010509

Catalog No. A30618

main product photo
CMLD010509 is a selective inhibitor of c-Myc, targeting the oncogenic translation program associated with multiple myeloma (MM). This compound demonstrates an IC50 of less than 10 nM in various MM cell lines and effectively induces apoptosis. CMLD010509 operates through a phosphorylation-independent mechanism, making it a valuable tool for studying the role of translation in oncogenesis and developing targeted therapeutic strategies in MM research.
Chemical Information
Catalog NumA30618
M. Wt556.40
FormulaC27H26BrNO7
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.256497-58-2
SynonymsSDS-1-021
SMILESO=C([C@H]([C@H]1C2=CC=CC=C2)[C@@H](O)[C@]3(O)[C@@]1(C4=CC=C(Br)C=C4)OC5=CC(OC)=CC(OC)=C35)NOC
Biological Activity
DescriptionCMLD010509 is a selective inhibitor of c-Myc, targeting the oncogenic translation program associated with multiple myeloma (MM). This compound demonstrates an IC50 of less than 10 nM in various MM cell lines and effectively induces apoptosis. CMLD010509 operates through a phosphorylation-independent mechanism, making it a valuable tool for studying the role of translation in oncogenesis and developing targeted therapeutic strategies in MM research.
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