Product Data Sheet

PAK4-IN-2

Catalog No. A30655

main product photo
PAK4-IN-2 is a potent inhibitor of the p21-activated kinase 4 (PAK4), exhibiting an IC50 value of 2.7 nM. This compound effectively induces cell cycle arrest at the G0/G1 phase and promotes apoptosis in MV4-11 cancer cells. PAK4-IN-2 is suitable for investigations into cancer biology and therapeutic development targeting PAK4 signaling pathways.
Chemical Information
Catalog NumA30655
M. Wt356.85
FormulaC18H21ClN6
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2488706-33-6
Synonyms
SMILESClC1=CC(NC2=NC(N[C@H]3CC[C@@H](N)CC3)=C4C(NC=C4)=N2)=CC=C1
Biological Activity
DescriptionPAK4-IN-2 is a potent inhibitor of the p21-activated kinase 4 (PAK4), exhibiting an IC50 value of 2.7 nM. This compound effectively induces cell cycle arrest at the G0/G1 phase and promotes apoptosis in MV4-11 cancer cells. PAK4-IN-2 is suitable for investigations into cancer biology and therapeutic development targeting PAK4 signaling pathways.
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