Product Data Sheet
Naratuximab emtansine
Catalog No. A30689
Naratuximab emtansine is a CD37-targeted antibody-drug conjugate (ADC) that combines a humanized IgG1 monoclonal antibody with the microtubule disruptor DM1. This compound exhibits high affinity and specificity for the CD37 antigen, facilitating internalization and subsequent release of DM1 intracellularly. By disrupting microtubule assembly, Naratuximab emtansine leads to cell cycle arrest and apoptosis, making it a valuable tool for research in targeted cancer therapies and hematological malignancies.
Chemical Information
| Catalog Num | A30689 |
|---|---|
| M. Wt | |
| Formula | |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1607824-64-5 |
| Synonyms | IMGN529; Debio 1562 |
| SMILES | [Naratuximab emtansine] |
Biological Activity
| Description | Naratuximab emtansine is a CD37-targeted antibody-drug conjugate (ADC) that combines a humanized IgG1 monoclonal antibody with the microtubule disruptor DM1. This compound exhibits high affinity and specificity for the CD37 antigen, facilitating internalization and subsequent release of DM1 intracellularly. By disrupting microtubule assembly, Naratuximab emtansine leads to cell cycle arrest and apoptosis, making it a valuable tool for research in targeted cancer therapies and hematological malignancies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
