Product Data Sheet
Diclofenac-d4
Catalog No. A30733
Diclofenac-d4 is a deuterated form of Diclofenac, a potent nonselective cyclooxygenase (COX) inhibitor. It exhibits IC50 values of 4 nM for COX-1 and 1.3 nM for COX-2 in CHO cells, demonstrating its high efficacy in reducing inflammation. Additionally, Diclofenac has been shown to induce apoptosis in neural stem cells (NSCs) through the activation of the caspase cascade, making it valuable for research in both anti-inflammatory treatments and neurobiology studies.
Chemical Information
| Catalog Num | A30733 |
|---|---|
| M. Wt | 300.17 |
| Formula | C14H7D4Cl2NO2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 153466-65-0 |
| Synonyms | |
| SMILES | OC(CC(C([2H])=C([2H])C([2H])=C1[2H])=C1NC2=C(C=CC=C2Cl)Cl)=O |
Biological Activity
| Description | Diclofenac-d4 is a deuterated form of Diclofenac, a potent nonselective cyclooxygenase (COX) inhibitor. It exhibits IC50 values of 4 nM for COX-1 and 1.3 nM for COX-2 in CHO cells, demonstrating its high efficacy in reducing inflammation. Additionally, Diclofenac has been shown to induce apoptosis in neural stem cells (NSCs) through the activation of the caspase cascade, making it valuable for research in both anti-inflammatory treatments and neurobiology studies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
