Product Data Sheet
Damnacanthal
Catalog No. A30760
Damnacanthal is an anthraquinone that primarily functions as an apoptosis inducer through selective inhibition of p56lck tyrosine kinase activity. Demonstrating significant anticancer properties, Damnacanthal effectively inhibits p56lck autophosphorylation and the phosphorylation of exogenous substrates, with IC50 values of 46 nM and 220 nM, respectively. Additionally, Damnacanthal exhibits antinociceptive and anti-inflammatory effects in murine models, along with antifungal activity against Candida albicans. This compound is valuable for research into cancer biology and related therapeutic pathways.
Chemical Information
| Catalog Num | A30760 |
|---|---|
| M. Wt | 282.25 |
| Formula | C16H10O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 477-84-9 |
| Synonyms | |
| SMILES | O=CC(C(OC)=C1C2=O)=C(O)C=C1C(C3=C2C=CC=C3)=O |
Biological Activity
| Description | Damnacanthal is an anthraquinone that primarily functions as an apoptosis inducer through selective inhibition of p56lck tyrosine kinase activity. Demonstrating significant anticancer properties, Damnacanthal effectively inhibits p56lck autophosphorylation and the phosphorylation of exogenous substrates, with IC50 values of 46 nM and 220 nM, respectively. Additionally, Damnacanthal exhibits antinociceptive and anti-inflammatory effects in murine models, along with antifungal activity against Candida albicans. This compound is valuable for research into cancer biology and related therapeutic pathways. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
