Product Data Sheet
Tofacitinib-d3 citrate
Catalog No. A30838
Tofacitinib-d3 citrate is a deuterated form of Tofacitinib citrate, serving as a stable isotope labeling reagent. This compound functions as a selective inhibitor of Janus kinases (JAK1, JAK2, and JAK3) with IC50 values of 1 nM, 20 nM, and 112 nM, respectively. Tofacitinib citrate exhibits significant antibacterial, antifungal, and antiviral activities, making it valuable for studies in immunology, infectious disease, and pharmacology. Its isotopic labeling allows for precise tracking and quantification in biological research.
Chemical Information
| Catalog Num | A30838 |
|---|---|
| M. Wt | 507.51 |
| Formula | C22H25D3N6O8 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2701680-77-3 |
| Synonyms | Tasocitinib-d3 citrate; CP-690550-d3 citrate |
| SMILES | O=C(CC#N)N1C[C@H](N(C2=C3C(NC=C3)=NC=N2)C([2H])([2H])[2H])[C@H](C)CC1.O=C(CC(C(O)=O)(O)CC(O)=O)O |
Biological Activity
| Description | Tofacitinib-d3 citrate is a deuterated form of Tofacitinib citrate, serving as a stable isotope labeling reagent. This compound functions as a selective inhibitor of Janus kinases (JAK1, JAK2, and JAK3) with IC50 values of 1 nM, 20 nM, and 112 nM, respectively. Tofacitinib citrate exhibits significant antibacterial, antifungal, and antiviral activities, making it valuable for studies in immunology, infectious disease, and pharmacology. Its isotopic labeling allows for precise tracking and quantification in biological research. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
