Product Data Sheet
UZH1
Catalog No. A30881
UZH1 is a METTL3 inhibitor that comprises a racemic mixture of UZH1a and UZH1b. UZH1a is a highly selective inhibitor, displaying an IC50 of 280 nM, while UZH1b shows minimal activity with an IC50 of 28 µM. UZH1 serves as an effective tool for epitranscriptomic modulation of cellular processes and demonstrates antitumor activity. Additionally, UZH1 can be utilized as a chemical probe for in-depth investigations of METTL3's role in various biological contexts.
Chemical Information
| Catalog Num | A30881 |
|---|---|
| M. Wt | 558.71 |
| Formula | C32H42N6O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2925713-02-4 |
| Synonyms | |
| SMILES | O=C(NCC1(O)CN(C2=NC=NC(NCC3=CC=CC=C3)=C2)CCC1)C4=CC=C(CN5CCC(C)(C)CC5)C=C4O |
Biological Activity
| Description | UZH1 is a METTL3 inhibitor that comprises a racemic mixture of UZH1a and UZH1b. UZH1a is a highly selective inhibitor, displaying an IC50 of 280 nM, while UZH1b shows minimal activity with an IC50 of 28 µM. UZH1 serves as an effective tool for epitranscriptomic modulation of cellular processes and demonstrates antitumor activity. Additionally, UZH1 can be utilized as a chemical probe for in-depth investigations of METTL3's role in various biological contexts. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
