Product Data Sheet
p,p'-DDD
Catalog No. A30912
p,p'-DDD (4,4'-DDD) is an organochlorine insecticide and a significant metabolite of p,p'-DDT, functioning primarily as an agonist of estrogen receptors α and β (ERα and ERβ). This compound has been shown to increase DNA damage, promote apoptosis, and induce necrosis in peripheral blood cells. Additionally, p,p'-DDD stimulates cell proliferation in SKBR3 breast cancer cells and activates the AP-1 transcription factor. Research also indicates that it can reduce sleep durations induced by barbiturates and steroids in rodent models.
Chemical Information
| Catalog Num | A30912 |
|---|---|
| M. Wt | 320.04 |
| Formula | C14H10Cl4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 72-54-8 |
| Synonyms | 4,4'-DDD; p,p'-Dichlorodiphenyl dichloroethane |
| SMILES | ClC(Cl)C(C1=CC=C(Cl)C=C1)C2=CC=C(Cl)C=C2 |
Biological Activity
| Description | p,p'-DDD (4,4'-DDD) is an organochlorine insecticide and a significant metabolite of p,p'-DDT, functioning primarily as an agonist of estrogen receptors α and β (ERα and ERβ). This compound has been shown to increase DNA damage, promote apoptosis, and induce necrosis in peripheral blood cells. Additionally, p,p'-DDD stimulates cell proliferation in SKBR3 breast cancer cells and activates the AP-1 transcription factor. Research also indicates that it can reduce sleep durations induced by barbiturates and steroids in rodent models. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
