Product Data Sheet
Tamoxifen-d5
Catalog No. A30918
Tamoxifen-d5 is a deuterated form of Tamoxifen, a selective estrogen receptor modulator (SERM) known for its oral bioavailability. This compound acts as a potent activator of Heat Shock Protein 90 (Hsp90), enhancing its ATPase activity, which is crucial for protein folding and cellular response to stress. Tamoxifen-d5 is valuable in research focusing on hormone-responsive cancers, Hsp90-dependent pathways, and pharmacokinetic studies involving deuterium labeling.
Chemical Information
| Catalog Num | A30918 |
|---|---|
| M. Wt | 376.55 |
| Formula | C26H24D5NO |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 157698-32-3 |
| Synonyms | ICI 47699-d5; (Z)-Tamoxifen-d5; trans-Tamoxifen-d5 |
| SMILES | [2H]C([2H])([2H])C([2H])([2H])/C(C1=CC=CC=C1)=C(C2=CC=C(OCCN(C)C)C=C2)\C3=CC=CC=C3 |
Biological Activity
| Description | Tamoxifen-d5 is a deuterated form of Tamoxifen, a selective estrogen receptor modulator (SERM) known for its oral bioavailability. This compound acts as a potent activator of Heat Shock Protein 90 (Hsp90), enhancing its ATPase activity, which is crucial for protein folding and cellular response to stress. Tamoxifen-d5 is valuable in research focusing on hormone-responsive cancers, Hsp90-dependent pathways, and pharmacokinetic studies involving deuterium labeling. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
