Product Data Sheet

L-Asparagine-13C4 monohydrate

Catalog No. A30927

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L-Asparagine-13C4 monohydrate is a stable isotope-labeled form of L-Asparagine, specifically designated for metabolic tracing applications. This amino acid is critical for leukemic cell survival and serves as a substrate for L-Asparaginase, an enzyme that depletes asparagine and glutamine, thereby inhibiting protein biosynthesis and inducing apoptosis in lymphoblasts. The utilization of L-Asparagine-13C4 can facilitate research into the mechanisms of acute lymphoblastic leukemia, making it a valuable tool for understanding cancer cell metabolism and exploring potential therapeutic strategies.
Chemical Information
Catalog NumA30927
M. Wt154.10
Formula13C4H10N2O4
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.286460-82-0
Synonyms(-)-Asparagine-13C4 monohydrate; Asn-13C4 monohydrate; Asparamide-13C4 monohydrate
SMILESN[13C]([13CH2][13C@H](N)[13C](O)=O)=O.[H]O[H]
Biological Activity
DescriptionL-Asparagine-13C4 monohydrate is a stable isotope-labeled form of L-Asparagine, specifically designated for metabolic tracing applications. This amino acid is critical for leukemic cell survival and serves as a substrate for L-Asparaginase, an enzyme that depletes asparagine and glutamine, thereby inhibiting protein biosynthesis and inducing apoptosis in lymphoblasts. The utilization of L-Asparagine-13C4 can facilitate research into the mechanisms of acute lymphoblastic leukemia, making it a valuable tool for understanding cancer cell metabolism and exploring potential therapeutic strategies.
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SHIPPING AND STORAGE
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