Product Data Sheet
Melatonin-d7
Catalog No. A30948
Melatonin-d7 is a stable isotope-labeled form of melatonin, primarily known for its role as a hormone that activates melatonin receptors. This compound exhibits significant antioxidative and anti-inflammatory effects, contributing to sleep regulation. Additionally, melatonin-d7 is identified as a selective inhibitor of ATF-6, inducing apoptosis in human hepatoma cells through the downregulation of COX-2. In research applications, it has been shown to mitigate palmitic acid-induced apoptosis in mouse granulosa cells by modulating endoplasmic reticulum stress.
Chemical Information
| Catalog Num | A30948 |
|---|---|
| M. Wt | 239.32 |
| Formula | C13H9D7N2O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 615251-68-8 |
| Synonyms | N-Acetyl-5-methoxytryptamine-d7 |
| SMILES | [2H]C([2H])([2H])C(NC([2H])([2H])C([2H])([2H])C(C1=C2)=CNC1=CC=C2OC)=O |
Biological Activity
| Description | Melatonin-d7 is a stable isotope-labeled form of melatonin, primarily known for its role as a hormone that activates melatonin receptors. This compound exhibits significant antioxidative and anti-inflammatory effects, contributing to sleep regulation. Additionally, melatonin-d7 is identified as a selective inhibitor of ATF-6, inducing apoptosis in human hepatoma cells through the downregulation of COX-2. In research applications, it has been shown to mitigate palmitic acid-induced apoptosis in mouse granulosa cells by modulating endoplasmic reticulum stress. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
