Product Data Sheet
Amitriptyline-d6 hydrochloride
Catalog No. A30971
Amitriptyline-d6 hydrochloride is a deuterium-labeled form of the tricyclic antidepressant amitriptyline hydrochloride, primarily targeting the serotonin transporter (SERT) and norepinephrine transporter (NET) to enhance levels of serotonin and norepinephrine in the synaptic cleft. This compound exhibits key biological activities, including antidepressant, analgesic, and neurotrophic effects, due to its interaction with various receptors such as α2A, TrkA, and TrkB. Additionally, it demonstrates anti-inflammatory properties and influences cellular processes such as angiogenesis and apoptosis. Amitriptyline-d6 hydrochloride can be utilized in research applications related to antidepressant pharmacology and the study of receptor interactions.
Chemical Information
| Catalog Num | A30971 |
|---|---|
| M. Wt | 319.90 |
| Formula | C20H18D6ClN |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 203645-63-0 |
| Synonyms | |
| SMILES | [2H]C([2H])([2H])N(C([2H])([2H])[2H])CC/C=C1C2=CC=CC=C2CCC3=CC=CC=C3/1.Cl |
Biological Activity
| Description | Amitriptyline-d6 hydrochloride is a deuterium-labeled form of the tricyclic antidepressant amitriptyline hydrochloride, primarily targeting the serotonin transporter (SERT) and norepinephrine transporter (NET) to enhance levels of serotonin and norepinephrine in the synaptic cleft. This compound exhibits key biological activities, including antidepressant, analgesic, and neurotrophic effects, due to its interaction with various receptors such as α2A, TrkA, and TrkB. Additionally, it demonstrates anti-inflammatory properties and influences cellular processes such as angiogenesis and apoptosis. Amitriptyline-d6 hydrochloride can be utilized in research applications related to antidepressant pharmacology and the study of receptor interactions. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
