Product Data Sheet
Imipramine-d4 hydrochloride
Catalog No. A30972
Imipramine-d4 hydrochloride is a deuterium-labeled form of the tricyclic antidepressant, Imipramine hydrochloride. This compound primarily acts as a Fascin1 inhibitor, exhibiting notable antitumor activity. Additionally, Imipramine-d4 hydrochloride inhibits the serotonin transporter with an IC50 of 32 nM and has been shown to stimulate autophagy in U-87MG glioma cells while inducing apoptosis in HL-60 cells. Its neuroprotective and immunomodulatory properties further enhance its relevance in various biological research applications.
Chemical Information
| Catalog Num | A30972 |
|---|---|
| M. Wt | 320.89 |
| Formula | C19H21D4ClN2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 61361-33-9 |
| Synonyms | |
| SMILES | CN(C)CCCN1C2=C([2H])C=C([2H])C=C2CCC3=CC([2H])=CC([2H])=C31.Cl[H] |
Biological Activity
| Description | Imipramine-d4 hydrochloride is a deuterium-labeled form of the tricyclic antidepressant, Imipramine hydrochloride. This compound primarily acts as a Fascin1 inhibitor, exhibiting notable antitumor activity. Additionally, Imipramine-d4 hydrochloride inhibits the serotonin transporter with an IC50 of 32 nM and has been shown to stimulate autophagy in U-87MG glioma cells while inducing apoptosis in HL-60 cells. Its neuroprotective and immunomodulatory properties further enhance its relevance in various biological research applications. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
