Product Data Sheet
Methylisothiazolinone-d3 hydrochloride
Catalog No. A30974
Methylisothiazolinone-d3 hydrochloride is a deuterium-labeled derivative of Methylisothiazolinone hydrochloride, serving as a stable isotope for research applications. It acts as a bacterial and fungal inhibitor and preservative, while also functioning as a sensitizer. This compound is known to activate matrix metalloproteinases (MMPs) in human bronchial epithelial cells, leading to apoptosis and an inflammatory response. Additionally, Methylisothiazolinone can promote atopic dermatitis development in murine models by interfering with Th2/Th17 immune pathways and can induce mitochondrial damage in the endothelium of rat cerebral blood vessels.
Chemical Information
| Catalog Num | A30974 |
|---|---|
| M. Wt | 154.63 |
| Formula | C4H3D3ClNOS |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1329509-49-0 |
| Synonyms | |
| SMILES | O=C1N(SC=C1)C([2H])([2H])[2H].Cl |
Biological Activity
| Description | Methylisothiazolinone-d3 hydrochloride is a deuterium-labeled derivative of Methylisothiazolinone hydrochloride, serving as a stable isotope for research applications. It acts as a bacterial and fungal inhibitor and preservative, while also functioning as a sensitizer. This compound is known to activate matrix metalloproteinases (MMPs) in human bronchial epithelial cells, leading to apoptosis and an inflammatory response. Additionally, Methylisothiazolinone can promote atopic dermatitis development in murine models by interfering with Th2/Th17 immune pathways and can induce mitochondrial damage in the endothelium of rat cerebral blood vessels. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
