Product Data Sheet

Nur77 modulator 1

Catalog No. A31000

main product photo
Nur77 Modulator 1 is an effective modulator of Nur77, characterized by a binding affinity of KD = 3.58 μM. This compound up-regulates Nur77 expression and influences its sub-cellular localization, leading to Nur77-dependent endoplasmic reticulum (ER) stress and autophagy, ultimately promoting apoptotic processes in cells. Its notable anti-hepatoma activity makes it a valuable tool for research in cancer biology and cellular stress responses.
Chemical Information
Catalog NumA31000
M. Wt495.60
FormulaC28H25N5O2S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2469975-55-9
Synonyms
SMILESCC1=NC2=C(OC)C=CC=C2C(NC3=CC4=C(NC(C(N/N=C/C5=CC=C(SC)C=C5)=O)=C4)C=C3)=C1
Biological Activity
DescriptionNur77 Modulator 1 is an effective modulator of Nur77, characterized by a binding affinity of KD = 3.58 μM. This compound up-regulates Nur77 expression and influences its sub-cellular localization, leading to Nur77-dependent endoplasmic reticulum (ER) stress and autophagy, ultimately promoting apoptotic processes in cells. Its notable anti-hepatoma activity makes it a valuable tool for research in cancer biology and cellular stress responses.
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SHIPPING AND STORAGE
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