Product Data Sheet
Azurin p28 peptide
Catalog No. A31019
Azurin p28 peptide is an antitumor peptide that primarily targets and stabilizes the tumor suppressor protein p53. By forming a complex with p53, it reduces proteasomal degradation, leading to apoptosis or cell cycle arrest in p53-positive tumors. Additionally, Azurin p28 peptide exhibits antiangiogenic properties by inhibiting the phosphorylation of key signaling molecules, including VEGFR-2, FAK, and Akt, thereby impeding tumor growth and vascularization. This peptide is valuable in cancer research focusing on p53-mediated pathways and antiangiogenic strategies.
Chemical Information
| Catalog Num | A31019 |
|---|---|
| M. Wt | 2914.18 |
| Formula | C122H197N31O47S2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 897026-25-4 |
| Synonyms | |
| SMILES | C([C@@H](NC([C@@H](NC([C@H](CC1=CC=C(O)C=C1)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC(C)C)N)=O)CO)=O)[C@@H](C)O)=O)C)=O)C)=O)CC(O)=O)=O)CCSC)=O)CCC(N)=O)=O)=O)[C@@H](C)C)=O)C(C)C)=O)[C@@H](C)O)=O)CC(O)=O)=O)=O)CCSC)=O)C)=O)CO)=O)=O)CC(C)C)=O)CC(O)=O)=O)CCCCN)=O)CC(O)=O)=O)=O)CC(C)C)=O)CCCCN)(=O)N2[C@H](C(N[C@H](C(N[C@@H](CC(O)=O)C(O)=O)=O)CC(O)=O)=O)CCC2 |
Biological Activity
| Description | Azurin p28 peptide is an antitumor peptide that primarily targets and stabilizes the tumor suppressor protein p53. By forming a complex with p53, it reduces proteasomal degradation, leading to apoptosis or cell cycle arrest in p53-positive tumors. Additionally, Azurin p28 peptide exhibits antiangiogenic properties by inhibiting the phosphorylation of key signaling molecules, including VEGFR-2, FAK, and Akt, thereby impeding tumor growth and vascularization. This peptide is valuable in cancer research focusing on p53-mediated pathways and antiangiogenic strategies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
