Product Data Sheet

UC-514321

Catalog No. A31037

main product photo
UC-514321 is a potent inhibitor of STAT3 and STAT5, effectively repressing TET1 expression without affecting TET2 or TET3. This compound demonstrates significant promise for the treatment of acute myeloid leukemia (AML) in both in vitro and in vivo settings. Its selective action and low toxicity profile make it a valuable tool for research in cancer therapeutics.
Chemical Information
Catalog NumA31037
M. Wt441.56
FormulaC26H35NO5
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.299420-83-0
Synonyms
SMILESOC1=C(C=C2OCOC2=C1)C(N3CCOCC3)C4=CC(C(C)(C)C)=C(C(C(C)(C)C)=C4)O
Biological Activity
DescriptionUC-514321 is a potent inhibitor of STAT3 and STAT5, effectively repressing TET1 expression without affecting TET2 or TET3. This compound demonstrates significant promise for the treatment of acute myeloid leukemia (AML) in both in vitro and in vivo settings. Its selective action and low toxicity profile make it a valuable tool for research in cancer therapeutics.
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