Product Data Sheet
Physalin B
Catalog No. A31055
Physalin B is a potent autophagy inducer derived from Cape gooseberry, known for its steroidal properties. It has been shown to induce cell cycle arrest and promote apoptosis in breast cancer cells by modulating the p53-dependent apoptotic pathway. Additionally, Physalin B inhibits the ubiquitin-proteasome pathway and elicits an incomplete autophagic response in human colon cancer cells in vitro, making it a valuable tool for cancer research and the study of autophagic mechanisms.
Chemical Information
| Catalog Num | A31055 |
|---|---|
| M. Wt | 510.53 |
| Formula | C28H30O9 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 23133-56-4 |
| Synonyms | |
| SMILES | C[C@@]([C@H](OC1=O)C2)(OC3=O)[C@](O[C@@]45C6=O)([C@@]3(CC[C@@]7([H])[C@@]4([H])CC=C(CC=C8)[C@@]7(C8=O)C)O)[C@]6([H])[C@]2([C@@]1([H])CO5)C |
Biological Activity
| Description | Physalin B is a potent autophagy inducer derived from Cape gooseberry, known for its steroidal properties. It has been shown to induce cell cycle arrest and promote apoptosis in breast cancer cells by modulating the p53-dependent apoptotic pathway. Additionally, Physalin B inhibits the ubiquitin-proteasome pathway and elicits an incomplete autophagic response in human colon cancer cells in vitro, making it a valuable tool for cancer research and the study of autophagic mechanisms. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
