Verrucarin J
Catalog No. A31096

Verrucarin J, a metabolite derived from the Myrothecium fungus, primarily targets the induction of reactive oxygen species (ROS) in various cancer cell lines. It has demonstrated significant apoptotic activity in A549, HCT 116, and SW-620 cells. Additionally, Verrucarin J exhibits antifungal properties against Candida albicans and Mucor miehei, and effectively inhibits the arenavirus Junin (JUNV) with an IC50 value of 1.2 ng/mL, highlighting its potential for research in oncology and virology.
Chemical Information
| Catalog Num | A31096 |
|---|---|
| M. Wt | 484.54 |
| Formula | C27H32O8 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 4643-58-7 |
| Synonyms | Muconomycin B |
| SMILES | CC1=C[C@@H]2[C@]3(COC(/C=C(C)/CCOC(/C=C/C=C\C(OC4[C@]3(C)[C@@]5([C@H](O2)C4)CO5)=O)=O)=O)CC1 |
Biological Activity
| Description | Verrucarin J, a metabolite derived from the Myrothecium fungus, primarily targets the induction of reactive oxygen species (ROS) in various cancer cell lines. It has demonstrated significant apoptotic activity in A549, HCT 116, and SW-620 cells. Additionally, Verrucarin J exhibits antifungal properties against Candida albicans and Mucor miehei, and effectively inhibits the arenavirus Junin (JUNV) with an IC50 value of 1.2 ng/mL, highlighting its potential for research in oncology and virology. |
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


