Product Data Sheet
XL44
Catalog No. A31151
XL44 is an apoptosis inducer that targets hRpn13, facilitating hRpn13-dependent programmed cell death. This compound reduces cell viability through a PCLAF-dependent mechanism, promoting the ubiquitin-dependent degradation of hRpn13Pru and the ubiquitin-independent degradation of specific proteins containing KEN boxes. XL44 is utilized in research applications focused on understanding apoptosis pathways and protein degradation mechanisms.
Chemical Information
| Catalog Num | A31151 |
|---|---|
| M. Wt | 388.39 |
| Formula | C23H17FN2O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2637949-91-6 |
| Synonyms | |
| SMILES | O=C(C1=CC=C(OC)C=C1)NC2=CC=CC(/C=C3C(NC4=C\3C=C(F)C=C4)=O)=C2 |
Biological Activity
| Description | XL44 is an apoptosis inducer that targets hRpn13, facilitating hRpn13-dependent programmed cell death. This compound reduces cell viability through a PCLAF-dependent mechanism, promoting the ubiquitin-dependent degradation of hRpn13Pru and the ubiquitin-independent degradation of specific proteins containing KEN boxes. XL44 is utilized in research applications focused on understanding apoptosis pathways and protein degradation mechanisms. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
