Thalidomide-O-C5-acid
Catalog No. A31246

Thalidomide-O-C5-acid is a synthesized E3 ligase ligand-linker conjugate designed to engage cereblon, a key target in the ubiquitin-proteasome system. This compound serves as a crucial component in PROTAC technology, facilitating targeted protein degradation. Its utility in research includes the development of novel therapeutic strategies aimed at modulating protein levels in various biological contexts.
Chemical Information
| Catalog Num | A31246 |
|---|---|
| M. Wt | 388.37 |
| Formula | C19H20N2O7 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2087490-48-8 |
| Synonyms | |
| SMILES | O=C(O)CCCCCOC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O |
Biological Activity
| Description | Thalidomide-O-C5-acid is a synthesized E3 ligase ligand-linker conjugate designed to engage cereblon, a key target in the ubiquitin-proteasome system. This compound serves as a crucial component in PROTAC technology, facilitating targeted protein degradation. Its utility in research includes the development of novel therapeutic strategies aimed at modulating protein levels in various biological contexts. |
|---|
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


