Product Data Sheet
Vorinostat-d5
Catalog No. A31248
Vorinostat-d5 is a deuterium-labeled form of Vorinostat, a potent pan-inhibitor of histone deacetylases (HDACs), specifically targeting HDAC1, HDAC2, and HDAC3 (Class I), HDAC7 (Class II), and HDAC11 (Class IV), with ID50 values of 10 nM and 20 nM for HDAC1 and HDAC3, respectively. It effectively induces apoptosis in cancer cells and serves as an inhibitor of human papillomavirus (HPV)-18 DNA amplification. Vorinostat-d5 is valuable for research applications focused on epigenetics, cancer therapy, and virology.
Chemical Information
| Catalog Num | A31248 |
|---|---|
| M. Wt | 269.35 |
| Formula | C14H15D5N2O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1132749-48-4 |
| Synonyms | SAHA-d5; Suberoylanilide hydroxamic acid-d5 |
| SMILES | O=C(NO)CCCCCCC(NC1=C([2H])C([2H])=C([2H])C([2H])=C1[2H])=O |
Biological Activity
| Description | Vorinostat-d5 is a deuterium-labeled form of Vorinostat, a potent pan-inhibitor of histone deacetylases (HDACs), specifically targeting HDAC1, HDAC2, and HDAC3 (Class I), HDAC7 (Class II), and HDAC11 (Class IV), with ID50 values of 10 nM and 20 nM for HDAC1 and HDAC3, respectively. It effectively induces apoptosis in cancer cells and serves as an inhibitor of human papillomavirus (HPV)-18 DNA amplification. Vorinostat-d5 is valuable for research applications focused on epigenetics, cancer therapy, and virology. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
