Product Data Sheet
5-Fluorouracil-15N2
Catalog No. A31260
5-Fluorouracil-15N2 is a stable isotope-labeled analogue of the chemotherapeutic agent 5-Fluorouracil (5-FU). It primarily targets thymidylate synthetase, inhibiting pyrimidine synthesis and leading to decreased intracellular dTTP levels, which induces apoptosis in cancer cells. Additionally, it has been noted for its potential to serve as a chemical sensitizer and exhibits inhibitory effects on HIV. This compound is valuable for research applications in cancer therapy and HIV studies.
Chemical Information
| Catalog Num | A31260 |
|---|---|
| M. Wt | 132.06 |
| Formula | C4H3F15N2O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 68941-95-7 |
| Synonyms | |
| SMILES | O=C1C(F)=C[15NH]C([15NH]1)=O |
Biological Activity
| Description | 5-Fluorouracil-15N2 is a stable isotope-labeled analogue of the chemotherapeutic agent 5-Fluorouracil (5-FU). It primarily targets thymidylate synthetase, inhibiting pyrimidine synthesis and leading to decreased intracellular dTTP levels, which induces apoptosis in cancer cells. Additionally, it has been noted for its potential to serve as a chemical sensitizer and exhibits inhibitory effects on HIV. This compound is valuable for research applications in cancer therapy and HIV studies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
