Product Data Sheet

Mepazine acetate

Catalog No. A31287

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Mepazine acetate is an apoptosis inducer that inhibits the protease activity of MALT1, making it a valuable tool for investigating the role of MALT1 in various biological processes. In studies with mouse bone marrow precursor cells, treatment with mepazine acetate significantly reduced RANK ligand (RANKL)-induced osteoclast formation and suppressed the expression of key osteoclast markers, including TRAP and feline hepsin K. Notably, its protective effects were found to be independent of MALT1 deficiency, suggesting the involvement of alternative mechanisms. This compound is essential for research focused on apoptosis, osteoclast differentiation, and related signaling pathways.
Chemical Information
Catalog NumA31287
M. Wt370.51
FormulaC21H26N2O2S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.24360-97-2
SynonymsPecazine acetate
SMILESO=C(C)O.CN(CCC1)CC1CN2C3=C(C=CC=C3)SC4=C2C=CC=C4
Biological Activity
DescriptionMepazine acetate is an apoptosis inducer that inhibits the protease activity of MALT1, making it a valuable tool for investigating the role of MALT1 in various biological processes. In studies with mouse bone marrow precursor cells, treatment with mepazine acetate significantly reduced RANK ligand (RANKL)-induced osteoclast formation and suppressed the expression of key osteoclast markers, including TRAP and feline hepsin K. Notably, its protective effects were found to be independent of MALT1 deficiency, suggesting the involvement of alternative mechanisms. This compound is essential for research focused on apoptosis, osteoclast differentiation, and related signaling pathways.
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