Product Data Sheet
Pim-1 kinase inhibitor 8
Catalog No. A31299
Pim-1 kinase inhibitor 8 is a selective inhibitor of the PIM-1 kinase, exhibiting an IC50 value of 14.3 nM. This compound effectively disrupts cellular proliferation and migration by inhibiting PIM-1, leading to the induction of apoptosis and autophagy. In vivo studies demonstrate its capability to inhibit solid tumor growth in Solid Ehrlich Carcinoma (SEC)-bearing mice. Pim-1 kinase inhibitor 8 is valuable for research focused on breast and liver cancer.
Chemical Information
| Catalog Num | A31299 |
|---|---|
| M. Wt | 275.30 |
| Formula | C14H17N3O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 916038-47-6 |
| Synonyms | |
| SMILES | N#CC1=C(OCC(N2CCOCC2)=O)N=C(C)C=C1C |
Biological Activity
| Description | Pim-1 kinase inhibitor 8 is a selective inhibitor of the PIM-1 kinase, exhibiting an IC50 value of 14.3 nM. This compound effectively disrupts cellular proliferation and migration by inhibiting PIM-1, leading to the induction of apoptosis and autophagy. In vivo studies demonstrate its capability to inhibit solid tumor growth in Solid Ehrlich Carcinoma (SEC)-bearing mice. Pim-1 kinase inhibitor 8 is valuable for research focused on breast and liver cancer. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
