Product Data Sheet
Lenalidomide-d5
Catalog No. A31300
Lenalidomide-d5 is a stable isotope-labeled derivative of Lenalidomide, an immunomodulatory compound that functions as a molecular glue. By acting as a ligand for the ubiquitin E3 ligase cereblon (CRBN), it facilitates the selective ubiquitination and subsequent degradation of the transcription factors IKZF1 and IKZF3. Lenalidomide-d5 is pivotal for research in cancer biology, particularly for investigating the mechanisms of action in mature B-cell lymphomas, including multiple myeloma, and for studying its effects on cytokine release from T cells.
Chemical Information
| Catalog Num | A31300 |
|---|---|
| M. Wt | 264.29 |
| Formula | C13H8D5N3O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1227162-34-6 |
| Synonyms | CC-5013-d5 |
| SMILES | O=C1N(C2([2H])C(NC(C([2H])([2H])C2([2H])[2H])=O)=O)CC3=C(N)C=CC=C31 |
Biological Activity
| Description | Lenalidomide-d5 is a stable isotope-labeled derivative of Lenalidomide, an immunomodulatory compound that functions as a molecular glue. By acting as a ligand for the ubiquitin E3 ligase cereblon (CRBN), it facilitates the selective ubiquitination and subsequent degradation of the transcription factors IKZF1 and IKZF3. Lenalidomide-d5 is pivotal for research in cancer biology, particularly for investigating the mechanisms of action in mature B-cell lymphomas, including multiple myeloma, and for studying its effects on cytokine release from T cells. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
