Product Data Sheet
Diclofenac-13C6 sodium
Catalog No. A31310
Diclofenac-13C6 sodium is a stable isotope-labeled derivative of Diclofenac, a potent and nonselective inhibitor of cyclooxygenases (COX-1 and COX-2). With IC50 values of 4 nM and 1.3 nM in human CHO cells, it exhibits strong anti-inflammatory activity. Additionally, Diclofenac sodium has been shown to induce apoptosis in neural stem cells through the activation of the caspase cascade, making it a valuable tool in biochemical and pharmacological research.
Chemical Information
| Catalog Num | A31310 |
|---|---|
| M. Wt | 324.09 |
| Formula | C813C6H10Cl2NNaO2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1261393-73-0 |
| Synonyms | GP 45840-13C6 |
| SMILES | O=C(O[Na])C[13C]([13CH]=[13CH][13CH]=[13CH]1)=[13C]1NC2=C(C=CC=C2Cl)Cl |
Biological Activity
| Description | Diclofenac-13C6 sodium is a stable isotope-labeled derivative of Diclofenac, a potent and nonselective inhibitor of cyclooxygenases (COX-1 and COX-2). With IC50 values of 4 nM and 1.3 nM in human CHO cells, it exhibits strong anti-inflammatory activity. Additionally, Diclofenac sodium has been shown to induce apoptosis in neural stem cells through the activation of the caspase cascade, making it a valuable tool in biochemical and pharmacological research. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
