Product Data Sheet
Thalidomide-5-methyl
Catalog No. A31319
Thalidomide-5-methyl functions as an E3 ligase ligand, specifically targeting cereblon (CRBN). This compound facilitates the recruitment of CRBN protein, enabling the development of PROTAC (proteolysis-targeting chimeras) for targeted protein degradation strategies. Thalidomide-5-methyl is a valuable tool in chemical biology and drug discovery research, particularly for studies related to targeted therapies and the modulation of protein stability.
Chemical Information
| Catalog Num | A31319 |
|---|---|
| M. Wt | 272.26 |
| Formula | C14H12N2O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 40313-92-6 |
| Synonyms | |
| SMILES | O=C1NC(C(CC1)N2C(C3=CC=C(C)C=C3C2=O)=O)=O |
Biological Activity
| Description | Thalidomide-5-methyl functions as an E3 ligase ligand, specifically targeting cereblon (CRBN). This compound facilitates the recruitment of CRBN protein, enabling the development of PROTAC (proteolysis-targeting chimeras) for targeted protein degradation strategies. Thalidomide-5-methyl is a valuable tool in chemical biology and drug discovery research, particularly for studies related to targeted therapies and the modulation of protein stability. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
