Product Data Sheet
L-Asparagine-13C4,15N2,d8
Catalog No. A31322
L-Asparagine-13C4,15N2,d8 is a stable isotope-labeled form of the amino acid L-Asparagine, enriched with carbon-13 and nitrogen-15 isotopes. This compound plays a critical role in cancer research, particularly in the study of leukemia, as it serves as a substrate for the enzyme L-Asparaginase, which depletes asparagine and glutamine levels in the body. By inhibiting RNA and DNA synthesis in lymphoblasts, L-Asparaginase induces apoptosis in leukemic cells, making L-Asparagine-13C4,15N2,d8 a valuable tool for understanding mechanisms of cancer cell growth and for investigating childhood acute lymphoblastic leukemia.
Chemical Information
| Catalog Num | A31322 |
|---|---|
| M. Wt | 146.12 |
| Formula | 13C4D8 15N2O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1217464-18-0 |
| Synonyms | |
| SMILES | [2H][15N]([2H])[13C]([13C]([2H])([2H])[13C@@]([15N]([2H])[2H])([2H])[13C](O[2H])=O)=O |
Biological Activity
| Description | L-Asparagine-13C4,15N2,d8 is a stable isotope-labeled form of the amino acid L-Asparagine, enriched with carbon-13 and nitrogen-15 isotopes. This compound plays a critical role in cancer research, particularly in the study of leukemia, as it serves as a substrate for the enzyme L-Asparaginase, which depletes asparagine and glutamine levels in the body. By inhibiting RNA and DNA synthesis in lymphoblasts, L-Asparaginase induces apoptosis in leukemic cells, making L-Asparagine-13C4,15N2,d8 a valuable tool for understanding mechanisms of cancer cell growth and for investigating childhood acute lymphoblastic leukemia. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
