Product Data Sheet
Sotetsuflavone
Catalog No. A31328
Sotetsuflavone is a flavonoid extracted from Cycas revolute, primarily targeting cancer cell migration and invasion. It has been shown to reverse epithelial-mesenchymal transition (EMT), induce apoptosis, and activate autophagy in A549 lung cancer cells. Additionally, Sotetsuflavone downregulates key factors such as HIF-1α, VEGF, angiostatin, MMP-9, and MMP-13, contributing to its anticancer properties. This compound is also investigated for its protective effects in models of Crohn's disease-like colitis, making it a valuable reagent for research in non-small cell lung cancer (NSCLC) and inflammatory bowel diseases.
Chemical Information
| Catalog Num | A31328 |
|---|---|
| M. Wt | 552.48 |
| Formula | C31H20O10 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2608-21-1 |
| Synonyms | |
| SMILES | O=C1C=C(C2=CC=C(O)C=C2)OC3=C(C4=CC(C5=CC(C6=C(O)C=C(O)C=C6O5)=O)=CC=C4O)C(OC)=CC(O)=C13 |
Biological Activity
| Description | Sotetsuflavone is a flavonoid extracted from Cycas revolute, primarily targeting cancer cell migration and invasion. It has been shown to reverse epithelial-mesenchymal transition (EMT), induce apoptosis, and activate autophagy in A549 lung cancer cells. Additionally, Sotetsuflavone downregulates key factors such as HIF-1α, VEGF, angiostatin, MMP-9, and MMP-13, contributing to its anticancer properties. This compound is also investigated for its protective effects in models of Crohn's disease-like colitis, making it a valuable reagent for research in non-small cell lung cancer (NSCLC) and inflammatory bowel diseases. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
