Product Data Sheet
MMRi64
Catalog No. A31334
MMRi64 is a selective inhibitor of the Mdm2-MdmX protein interactions. This compound downregulates Mdm2 and MdmX levels in leukemia cells, leading to increased accumulation of p53 and activation of the apoptotic pathways associated with p53. MMRi64 is a valuable tool for cancer research, particularly in the study of leukemias and lymphomas, where modulation of the p53 signaling axis is critical.
Chemical Information
| Catalog Num | A31334 |
|---|---|
| M. Wt | 410.30 |
| Formula | C22H17Cl2N3O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 430458-66-5 |
| Synonyms | |
| SMILES | OC1=C2N=CC=CC2=CC=C1C(C3=CC=CC(Cl)=C3Cl)NC4=NC=CC(C)=C4 |
Biological Activity
| Description | MMRi64 is a selective inhibitor of the Mdm2-MdmX protein interactions. This compound downregulates Mdm2 and MdmX levels in leukemia cells, leading to increased accumulation of p53 and activation of the apoptotic pathways associated with p53. MMRi64 is a valuable tool for cancer research, particularly in the study of leukemias and lymphomas, where modulation of the p53 signaling axis is critical. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
