Product Data Sheet
Tamoxifen-d3
Catalog No. A31341
Tamoxifen-d3 is a deuterium-labeled derivative of Tamoxifen, a selective estrogen receptor modulator (SERM) that primarily functions by inhibiting estrogen action in breast tissue while potentially activating it in other tissues such as bone, liver, and uterus. This compound serves as a powerful Hsp90 activator, enhancing ATPase activity, and exhibits inhibition of EBOV Zaire and Marburg viruses with IC50 values of 0.1 μM and 1.8 μM, respectively. Tamoxifen-d3 is used in various research applications including studies on autophagy, apoptosis induction, and gene knockout in CreER(T2) transgenic models.
Chemical Information
| Catalog Num | A31341 |
|---|---|
| M. Wt | 374.53 |
| Formula | C26H26D3NO |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 508201-30-7 |
| Synonyms | ICI 47699-d3; (Z)-Tamoxifen-d3; trans-Tamoxifen-d3 |
| SMILES | CC/C(C1=CC=CC=C1)=C(C2=CC=CC=C2)/C3=CC=C(C=C3)OCCN(C)C([2H])([2H])[2H] |
Biological Activity
| Description | Tamoxifen-d3 is a deuterium-labeled derivative of Tamoxifen, a selective estrogen receptor modulator (SERM) that primarily functions by inhibiting estrogen action in breast tissue while potentially activating it in other tissues such as bone, liver, and uterus. This compound serves as a powerful Hsp90 activator, enhancing ATPase activity, and exhibits inhibition of EBOV Zaire and Marburg viruses with IC50 values of 0.1 μM and 1.8 μM, respectively. Tamoxifen-d3 is used in various research applications including studies on autophagy, apoptosis induction, and gene knockout in CreER(T2) transgenic models. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
