Product Data Sheet

Nauclefine

Catalog No. A31343

main product photo
Nauclefine is an indole alkaloid derived from Nauclea officinalis, serving as a modulator of phosphodiesterase 3A (PDE3A). This compound has been shown to promote apoptosis in cancer cells via a PDE3A-SLFN12-dependent death pathway. Its biological activity makes Nauclefine a valuable tool for research into cancer therapeutics and the understanding of apoptotic mechanisms.
Chemical Information
Catalog NumA31343
M. Wt287.32
FormulaC18H13N3O
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.57103-51-2
Synonyms
SMILESO=C1C2=C(C=C3C4=C(CCN13)C5=C(C=CC=C5)N4)C=CN=C2
Biological Activity
DescriptionNauclefine is an indole alkaloid derived from Nauclea officinalis, serving as a modulator of phosphodiesterase 3A (PDE3A). This compound has been shown to promote apoptosis in cancer cells via a PDE3A-SLFN12-dependent death pathway. Its biological activity makes Nauclefine a valuable tool for research into cancer therapeutics and the understanding of apoptotic mechanisms.
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