Pyridinium bisretinoid A2E
Catalog No. A31365

Pyridinium bisretinoid A2E is an apoptosis inducer primarily found in lipofuscin within the retinal pigment epithelium. This compound triggers blue-light-induced apoptosis, facilitating autophagy and generating reactive oxygen species upon photoactivation. A2E is employed in research to investigate mechanisms underlying retinal degenerative diseases.
Chemical Information
| Catalog Num | A31365 |
|---|---|
| M. Wt | 592.92 |
| Formula | C42H58NO+ |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 173449-96-2 |
| Synonyms | A2E |
| SMILES | OCC[N+]1=CC=C(/C=C/C=C(C)/C=C/C2=C(C)CCCC2(C)C)C=C1/C=C(C)/C=C/C=C(C)/C=C/C3=C(C)CCCC3(C)C |
Biological Activity
| Description | Pyridinium bisretinoid A2E is an apoptosis inducer primarily found in lipofuscin within the retinal pigment epithelium. This compound triggers blue-light-induced apoptosis, facilitating autophagy and generating reactive oxygen species upon photoactivation. A2E is employed in research to investigate mechanisms underlying retinal degenerative diseases. |
|---|
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


