Product Data Sheet
ARF(26–44), cell-permeable
Catalog No. A31441
ARF(26–44), cell-permeable is a cell-penetrating peptide derived from the p14ARF tumor suppressor protein and functions as an inhibitor of FoxM1. This peptide exhibits marked anti-tumor activity, demonstrating the ability to increase apoptosis and decrease proliferation and angiogenesis in mouse models of hepatocellular carcinoma (HCC). ARF(26–44), cell-permeable serves as a valuable tool for research focusing on tumor therapy and the molecular mechanisms underlying cancer progression.
Chemical Information
| Catalog Num | A31441 |
|---|---|
| M. Wt | 3585.22 |
| Formula | C149H267N69O33S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 935732-44-8 |
| Synonyms | |
| SMILES | C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC1=CC=CC=C1)NC([C@@H](NC([C@H](NC([C@H](NC([C@H](NC([C@H](NC([C@H](NC([C@H](NC([C@H](NC([C@H](NC([C@@H](CCCNC(=N)N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCCN)=O)=O)[C@@H](C)C)=O)CCCNC(=N)N)=O)CO)=O)CCCNC(=N)N)=O)CCCNC(=N)N)(=O)N2[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC3=CC=CC=C3)C(N[C@H](C(N[C@@H](CC(N)=O)C(O)=O)=O)C(C)C)=O)=O)C)=O)CC(C)C)=O)C)=O)CS)=O)CO)=O)C)=O)[C@@H](C)O)=O)CCCNC(=N)N)=O)CCC2 |
Biological Activity
| Description | ARF(26–44), cell-permeable is a cell-penetrating peptide derived from the p14ARF tumor suppressor protein and functions as an inhibitor of FoxM1. This peptide exhibits marked anti-tumor activity, demonstrating the ability to increase apoptosis and decrease proliferation and angiogenesis in mouse models of hepatocellular carcinoma (HCC). ARF(26–44), cell-permeable serves as a valuable tool for research focusing on tumor therapy and the molecular mechanisms underlying cancer progression. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
