Product Data Sheet
AHR agonist 3
Catalog No. A31447
AHR Agonist 3 is a potent agonist of the aryl hydrocarbon receptor (AhR) that induces cell cycle arrest and apoptosis by activating tumor-suppressive transcriptional programs. It effectively inhibits the growth of stem cells in triple-negative breast cancer (TNBC) while demonstrating low cytotoxicity towards normal human primary cells. This compound is a valuable tool for cancer research, particularly in studies focused on TNBC and the mechanisms underlying AhR-mediated signaling pathways.
Chemical Information
| Catalog Num | A31447 |
|---|---|
| M. Wt | 270.28 |
| Formula | C18H10N2O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 23749-58-8 |
| Synonyms | |
| SMILES | C1=CC=C2C(=C1)N=C3C4=CC=CC5=C4C(=CC=C5)C(=O)N23 |
Biological Activity
| Description | AHR Agonist 3 is a potent agonist of the aryl hydrocarbon receptor (AhR) that induces cell cycle arrest and apoptosis by activating tumor-suppressive transcriptional programs. It effectively inhibits the growth of stem cells in triple-negative breast cancer (TNBC) while demonstrating low cytotoxicity towards normal human primary cells. This compound is a valuable tool for cancer research, particularly in studies focused on TNBC and the mechanisms underlying AhR-mediated signaling pathways. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
