Product Data Sheet
Idebenone-13C,d3
Catalog No. A31459
Idebenone-13C,d3 is a deuterium and carbon-13 labeled derivative of Idebenone, a potent mitochondrial protectant. It demonstrates neuroprotective effects and is relevant for studying neurodegenerative disorders such as Alzheimer's disease and Huntington's disease. Idebenone exhibits a dose-dependent inhibitory effect on the enzymatic metabolism of arachidonic acid, with an IC50 of 16.65 μM, and induces apoptotic cell death in SHSY-5Y human dopaminergic neuroblastoma cells. Additionally, it readily penetrates the blood-brain barrier, enhancing its potential in neurological research.
Chemical Information
| Catalog Num | A31459 |
|---|---|
| M. Wt | 342.45 |
| Formula | C1813CH27D3O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1189907-75-2 |
| Synonyms | |
| SMILES | O=C(C(CCCCCCCCCCO)=C(C1=O)C)C(OC)=C1O[13C]([2H])([2H])[2H] |
Biological Activity
| Description | Idebenone-13C,d3 is a deuterium and carbon-13 labeled derivative of Idebenone, a potent mitochondrial protectant. It demonstrates neuroprotective effects and is relevant for studying neurodegenerative disorders such as Alzheimer's disease and Huntington's disease. Idebenone exhibits a dose-dependent inhibitory effect on the enzymatic metabolism of arachidonic acid, with an IC50 of 16.65 μM, and induces apoptotic cell death in SHSY-5Y human dopaminergic neuroblastoma cells. Additionally, it readily penetrates the blood-brain barrier, enhancing its potential in neurological research. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
