Product Data Sheet

Risedronic acid-d4

Catalog No. A31470

main product photo
Risedronic acid-d4 is a deuterium-labeled derivative of Risedronic acid, a bisphosphonate known for its potent antiresorptive effects. This compound functions primarily by inhibiting osteoclast-mediated bone resorption and altering bone metabolism, making it essential for studies related to osteoporosis and related conditions. In addition, Risedronic acid has been shown to induce apoptosis and inhibit the transfer of farnesyl pyrophosphate groups in parasites, with notable activity against the blood-stage of Plasmodium falciparum (IC50 of 20.3 μM). Risedronic acid-d4 serves as a valuable tool in chemical research and metabolic studies.
Chemical Information
Catalog NumA31470
M. Wt287.14
FormulaC7H7D4NO7P2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1035438-80-2
SynonymsRisedronate-d4
SMILESC(CC=1C(=C(C(=NC1[2H])[2H])[2H])[2H])(P(=O)(O)O)(P(=O)(O)O)O
Biological Activity
DescriptionRisedronic acid-d4 is a deuterium-labeled derivative of Risedronic acid, a bisphosphonate known for its potent antiresorptive effects. This compound functions primarily by inhibiting osteoclast-mediated bone resorption and altering bone metabolism, making it essential for studies related to osteoporosis and related conditions. In addition, Risedronic acid has been shown to induce apoptosis and inhibit the transfer of farnesyl pyrophosphate groups in parasites, with notable activity against the blood-stage of Plasmodium falciparum (IC50 of 20.3 μM). Risedronic acid-d4 serves as a valuable tool in chemical research and metabolic studies.
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SHIPPING AND STORAGE
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